Important Changes to the 2026 Prohibited List

It was clarified in S1.1. that esters of the prohibited steroids are also prohibited.

Pegmolesatide was added as an example of a new EPO-mimetic agent.

The dosing intervals of salmeterol were revised to avoid potential ergogenic effects beyond therapeutic action. The maximum delivered dose is unchanged at 200 micrograms over 24 hours.

S4.1. 

2-Phenylbenzo[h]chromen-4-one, also known as ɑ-naphthoflavone or 7,8-benzoflavone, was added as an example of an aromatase inhibitor. This synthetic substance has been found in supplements.

 S4.4.

5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine, also known as BAM15, was added as an example of an activator of the AMP-activated protein kinase (AMPK). This synthetic substance has been found in supplements.

It was clarified that withdrawal of blood or blood components is prohibited except for 1) analytical purposes including medical tests or Doping Control, or for 2) donation purposes performed in a collection center accredited by the relevant regulatory authority of the country in which it operates. Note that Platelet-Rich Plasma (PRP) and related procedures remain not prohibited. 

The non-diagnostic use of carbon monoxide (CO) was added to the Prohibited Methods as a new section, M 1.4. It can increase erythropoiesis under certain conditions. The use of carbon monoxide for diagnostic purposes, such as total haemoglobin mass measurements or the determination of pulmonary diffusion capacity, is not prohibited. The current wording was chosen to differentiate between illicit use and the intake resulting from natural combustion processes (e.g. smoking), the environment (e. g. exhaust gases) or diagnostic procedures. 

Cell components (e.g. nuclei and organelles such as mitochondria and ribosomes) are added to the existing prohibition of using normal or genetically modified cells.

2-[Bis(4-fluorophenyl)methylsulfinyl]acetamide (flmodafinil) and 2-[bis(4-fluorophenyl) methylsulfinyl]-N-hydroxyacetamide (fladrafinil) were added to the S6.A list of nonspecified stimulants. These unapproved substances are potent analogs of modafinil and adrafinil, and are sold as supplements.

It is clarified that the urine monitoring of semaglutide includes also the monitoring of tirzepatide.